Quietus Spike Combos
Astarion, the Decadent + Quietus Spike
Blitzwing, Cruel Tormentor // Blitzwing, Adaptive Assailant + Quietus Spike
Goblin Sharpshooter + Quietus Spike
Quietus Spike + Archfiend of Despair
Quietus Spike + Warlock Class
Target opponent loses the game. Near-infinite lifeloss for target opponent.
All permanents on the battlefield. Quietus Spike attached to a creature that does not have summoning sickness. An opponent is unable to block and kill the creature with Quietus Spike attached. Warlock Class is level three.
Quietus Spike + Wound Reflection
Daryl, Hunter of Walkers + Thornbite Staff + Quietus Spike
Niv-Mizzet, the Firemind + Thornbite Staff + Quietus Spike
Near-infinite card draw. Near-infinite draw triggers. Destroy all nontoken creatures opponents control. Destroy all creatures that enter the battlefield under an opponent's control.
All permanents on the battlefield. Thornbite Staff and Quietus Spike attached to Niv-Mizzet. Niv-Mizzet does not have summoning sickness.